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. 2021 Sep 18;10(9):2475. doi: 10.3390/cells10092475

Table 2.

The impact of rapamycin-preconditioned ADSCs on liver biochemical parameters; ALT, AST and albumin, after cisplatin (Cis)-induced liver damage.

Group ALT (U/L) AST (U/L) Albumin (g/dL)
Control 48.16 ± 3.06 102 ± 14.71 3.35 ± 0.46
Cis 141.17 ± 8.56 * 268.67 ± 54.7 * 2.21 ± 0.61 *
Cis + ADSCs 104.33 ± 10.17 *,# 171 ± 71.35 *,# 2.63 ± 0.61 *,#
Cis + Rapa-ADSCs 85.83 ± 10.57 *,#,$ 114.67 ± 25.14 #,$ 3.08 ± 0.39 #,$

Cis, cisplatin (i.p. injection of 5 mg/kg in 0.9% saline) group; Cis + ADSCs, cisplatin group receiving ADSCs (one million cells, intravenous in tail vein); Cis + Rapa-ADSCs, cisplatin group receiving same number of ADSCs preconditioned with rapamycin (50 nM/L, 2 h prior to administration); * vs. control group (p < 0.01); # vs. Cis group (p < 0.01); $ vs. Cis+ADSCs group (p < 0.05).