Table 1.
Common infectious causes of uveitis and ME (in alphabetical order) along with treatment options.
Pathogen | Examples of Treatment Regimens |
---|---|
Bartonella sp. | Treatment remains controversial. Doxycycline 100 mg bid, alone or in combination with rifampin 300 mg bid; fluoroquinolones; or macrolides + steroids (e.g., Prednisolone 60 mg/day). Treatment should continue for a few weeks [5]. |
Borrelia sp. | Oral doxycycline 100 mg bid or intravenous ceftriaxone 1 g/day + steroids (e.g., oral prednisolone 1 mg/kg/day) [6]. |
Herpes sp. | Oral Valacyclovir 1–3 g/day or acyclovir 5 × 800 mg/day + intravitreal foscarnet 2.4 mg/0.1 mL twice weekly [7]. |
Mycobacterium tuberculosis | Multidrug therapy with four drugs (isoniazid, rifampin, ethambutol, and pyrazinamide) according to the country’s health policy [8]. |
Treponema pallidum (syphilis) | Intravenous aqueous penicillin G 18–24 MU/day every 4 h for 10–14 days + oral or intravenous steroids [9]. |
Toxocara sp. | Poor visual outcomes are common despite treatment: albendazole + steroids or vitrectomy in severe cases [10]. |
Toxoplasma sp. | Oral six-week course of clindamycin, pyrimethamine “ sulfadiazine, or trimethoprim/sulfamethoxazole + a tapering course of oral prednisolone (1 mg/kg) [11]. |