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Protein domain architecture in CaNB. Representative scheme of the EF-hand motifs in mammalian CaNB (HsCaNB-1) and in the obligate intracellular trypanosomatids (TcCaNB and LsppCaNB) showing the loops (numbered) containing the calcium affinity binding sites (green underline) with the different amino acids sequences on the right. The blue number over the box represents coordinating sites for Ca2+.
