Table 2.
Predicted CTL epitopes from S. aureus cell wall adherence proteins, SdrD and SdrE to design multi-epitope vaccine construct with their corresponding MHC Class I alleles and their immunogenic properties.
| Uniprot_ID | CTL Epitope | Alleles | Position | Score | Antigencity Score | Immunogenicity | Toxicity |
|---|---|---|---|---|---|---|---|
| O86488 | SGGAGQEVY | HLA-A*01:01 | 562 | 1.841 | 2.6468 | 0.08295 | Non-toxin |
| TLKNENGEV | HLA-A*02:01 | 822 | 4.4391 | 1.4625 | 0.102 | Non-toxin | |
| VTSGNDTEK | HLA-A*03:01 | 977 | 1.3119 | 2.012 | 0.08624 | Non-toxin | |
| DYRVEFSNL | HLA-A*24:02 | 629 | 0.9136 | 1.2237 | 0.12264 | Non-toxin | |
| NTRMRIAAV | HLA-A*26:01 | 229 | 1.307 | 0.7456 | 0.07166 | Non-toxin | |
| APKRLNTRM | HLA-B*07:02 | 224 | 0.0577 | 1.3117 | 0.02819 | Non-toxin | |
| DAKTESTTL | HLA-B*08:01 | 180 | 0.1135 | 1.9205 | 0.03373 | Non-toxin | |
| SKNDVEFNV | HLA-B*27:05 | 370 | 4.146 | 1.2062 | 0.24969 | Non-toxin | |
| SQITVDDKV | HLA-B*40:01 | 279 | 1.829 | 0.8785 | 0.03606 | Non-toxin | |
| SGDYFTIKY | HLA-B*58:01 | 289 | 3.063 | 1.6238 | 0.14034 | Non-toxin | |
| O86489 | KGDTMTINY | HLA-A*01:01 | 323 | 0.311 | 1.8025 | 0.02034 | Non-toxin |
| KTATEDTSV | HLA-A*02:01 | 142 | 3.039 | 1.4951 | 0.10624 | Non-toxin | |
| NTNNDVTTK | HLA-A*03:01 | 160 | 1.096 | 2.0046 | 0.10729 | Non-toxin | |
| KYSLGDYVW | HLA-A*24:02 | 830 | 0.105 | 0.4525 | 0.01002 | Non-toxin | |
| TSQNVTVDY | HLA-A*26:01 | 415 | 1.098 | 1.3552 | 0.08043 | Non-toxin | |
| TPAGYTPTV | HLA-B*07:02 | 786 | 0.194 | 0.9088 | 0.09306 | Non-toxin | |
| EQQIYVNPL | HLA-B*08:01 | 449 | 1.332 | 0.7245 | 0.11964 | Non-toxin | |
| KQTIEQQIY | HLA-B*27:05 | 445 | 4.415 | 0.8527 | 0.11498 | Non-toxin | |
| DKQTIEQQI | HLA-B*39:01 | 444 | 1.591 | 1.2024 | 0.05987 | Non-toxin | |
| IEQQIYVNP | HLA-B*40:01 | 448 | 2.472 | 0.7436 | 0.00302 | Non-toxin |