Table 10.
Compound 71 | Compound 76 | Compound 77 | ||||||
---|---|---|---|---|---|---|---|---|
Conc. (μM) | Vmax (μM−1s−1) | Km (μM) | Conc. (μM) | Vmax (μM−1s−1) | Km (μM) | Conc. (μM) | Vmax (μM−1s−1) | Km (μM) |
0 | 0.66 | 4.77 | ||||||
30 | 0.66 | 5.21 | 25 | 0.66 | 3.39 | 2.0 | 0.73 | 3.02 |
50 | 0.59 | 11.6 | 50 | 0.52 | 7.56 | 4.0 | 0.72 | 8.39 |
80 | 0.35 | 25.6 | 75 | 0.24 | 12.3 | 6.0 | 0.53 | 15.9 |
Km values are for CMP-Neu5Ac in the presence or the absence of the flavonoids.