Table 3.
Logistic regression analysis of factors used to separate patients with diabetes and heart failure from those without heart failure.
| Variables | Univariable Model | p-Value | Multivariable Model | p-Value |
|---|---|---|---|---|
| Crude OR [95% CI] | Adjusted OR [95% CI] | |||
| FGF21 (pg/mL) | 5.16 [2.19, 15.47] | 0.001 * | 8.80 [2.95, 36.30] | 0.001 * |
| Age (years) | 1.16 [0.71, 1.90] | 0.551 | 2.52 [1.12; 6.68] | 0.039 * |
| Gender (a) | 0.55 [0.20, 1.45] | 0.233 | 0.67 [0.16, 2.72] | 0.574 |
| BMI (kg/m2) | 1.50 [0.91, 2.55] | 0.118 | 0.69 [0.31, 1.44] | 0.340 |
| DBP (mmHG) | 1.45 [0.88, 2.50] | 0.157 | 1.20 [0.64, 2.38] | 0.573 |
| HbA1c (%) | 1.99 [1.14, 3.93] | 0.0267 * | 2.27 [1.19, 5.13] | 0.025 * |
| Previous MI | 2.32 [0.88, 6.40] | 0.094 | 3.81 [0.99, 17.19] | 0.061 |
FGF21 = fibroblast growth factor 21, BMI = body mass index, DBP = diastolic blood pressure, HbA1c = glycated hemoglobin; MI = myocardial infarction; * statistical significance: p < 0.05; Multivariable Model: FGF21 adjusted for demographic and clinical covariates; OR = odds ratio; (a) Reference category: Gender = F.