Figure 4.

Images of a mildly fibrotic and moderately inflamed bowel wall of a rat. (a) Axial T2-weighted imaging reveals a thickened bowel wall. (b) T₁ map shows that the T₁ value is 1304 ms (higher than the cutoff value of 1266 ms), thus indicating the presence of moderate-to-severe fibrosis. (c) The normalized magnetization transfer ratio (MTR) of the corresponding bowel wall is 0.68 (lower than the cutoff value of 0.72), which suggests the presence of none-to-mild fibrosis. (d) Hematoxylin and eosin (magnification = 4.93) and (e) Masson’s trichrome staining (magnification = 4.86) depicts moderate inflammation (score = 2) and mild fibrosis (score = 1). In this case, the diagnosis performance of the T₁ value is inferior to that of normalized MTR.