Table A1.
Complete data about patient’s characteristics.
| Patient Number | Age | Gender | Weight (kg) | Duration of Treatment (Days) | Dosage Schedule * [Treatment Indication] |
Total Amount of Drug Administered ** | Development of Hypertrichosis | Other Skin Side Effects | Systemic Side Effects |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 2 months | Male | 4.7 | 30 | 10 mg/day (2.12 mg/kg/day) [GER] |
300 mg | Yes | No | No |
| 2 | 7 months | Female | 7 | 120 | 8 mg/day (1.14 mg/kg/day) [GER] |
960 mg | Yes | No | No |
| 3 | 8 months | Male | 7.8 | 5 | 8 mg/day (1.03 mg/kg/day) [GER] |
40 mg | No | No | No |
| 4 | 1 year and 2 months | Female | 10.2 | 60 | 8.5 mg/day (0.85 mg/kg/day) [GER] |
510 mg | Yes | No | No |
| 5 | 1 year and 2 months | Female | 9 | 30 | 10 mg/day (1.11 mg/kg/day) [GER] |
300 mg | No | No | No |
| 6 | 1 year and 3 months | Female | 10 | 30 | 5 mg/day (0.5 mg/kg/day) [GER] |
150 mg | Yes | No | No |
| 7 | 1 year and 6 months | Male | 10 | 7 | 10 mg/day (1 mg/kg/day) [CORT-Kawasaki] |
70 mg | Yes | No | No |
| 8 | 1 year and 7 months | Male | 11 | 120 | 15 mg/day (1.36 mg/kg/day) [GER] |
1800 mg | Yes | Yes (changes in hair colour) | No |
| 9 | 1 year and 8 months | Male | 11.5 | 20 | 12 mg/day (1.04 mg/kg/day) [GER] |
240 mg | Yes | No | No |
| 10 | 1 year and 11 months | Female | 13 | 60 | 5 mg/day (0.38 mg/kg/day) [GER] |
300 mg | No | No | Yes (diarrhoea, anxiety) |
| 11 | 1 year and 11 months | Female | 10 | 120 | 15 mg/day (1.5 mg/kg/day) [GER] |
1800 mg | Yes | No | No |
| 12 | 6 years | Female | 22 | 5 | 20 mg/day (0.91 mg/kg/day) [H. Pylori] |
100 mg | No | No | Yes (headache, facial oedema) |
| 13 | 7 years | Male | 30 | 4 | 10 mg/day (0.33 mg/kg/day) [CORT-NS] |
40 mg | No | No | No |
| 14 | 7 years and 8 months | Male | 25 | 30 | 16 mg/day (0.64 mg/kg/day) [GER] |
480 mg | Yes | Yes (changes in hair colour) | Yes (severe asthenia) |
| 15 | 8 years and 5 months | Female | 27 | 30 | 20 mg/day (0.74 mg/kg/day) [H. Pylori] |
600 mg | Yes | No | No |
| 16 | 9 years and 2 months | Male | 30 | 12 | 20 mg/day (0.67 mg/kg/day) [GER] |
240 mg | No | No | No |
| 17 | 9 years and 3 months | Male | 29 | 15 | 20 mg/day (0.69 mg/kg/day) [H. Pylori] |
300 mg | Yes | No | No |
| 18 | 2 years | Male | 14.5 | 14 | 7.5mg / day (0.52 mg/kg/day) [GER] |
105 mg | Yes | No | No |
| 19 | 13 years | Male | 36.5 | 14 | 40 mg/day (1.10 mg/kg/day) [GER] |
560 mg | No | No | No |
| 20 | 2 years | Male | 9.6 | 40 | 4.5 mg/day (0.47 mg/kg/day) [GER] |
180 mg | Yes | No | No |
* Dosage schedule indicates the prescribed amount of omeprazole, which correspond to the amount of minoxidil. ** Total amount of drug administered is calculated: Amount of omeprazole prescribed per day x Days of treatment and indicates the actual amount of minoxidil taken by each patient. CORT: Gastric prophylaxis during steroid treatment for Kawasaki Disease or NS (Nefrotic Syndrome); GER: Gastroesophageal Reflux; H. Pylori: Eradication treatment for Helicobacter pylori.