Table A2.
Characteristics of the patients who developed hypertrichosis.
| Patient Number | Duration of Treatment (Days) | Total Amount of Drug Administered | Onset Latency Time of Hypertrichosis * (Days) |
Initial Location | Locations Finally Affected | Resolution (After 6 Months) | Latency Time for Resolution ** (Days) |
|---|---|---|---|---|---|---|---|
| 1 | 30 | 300 mg | 35 | Inferior limbs, pretibial location | Face, neck, back, superior/inferior limbs | No | - |
| 2 | 120 | 960 mg | 30 | Back | Face, back, superior/inferior limbs | Yes | 90 |
| 4 | 60 | 510 mg | 30 | Forehead | Face, neck, back, superior limbs | Yes | 90 |
| 6 | 30 | 150 mg | 15 | Forehead and temples | Face, chest, back, abdomen, superior/inferior limbs | No | - |
| 7 | 7 | 70 mg | 15 | Forehead, temples, superior lip | Face, back | Yes | 50 |
| 8 | 120 | 1800 mg | 30 | Forehead | Face, neck, chest, back, superior/inferior limbs | No | - |
| 9 | 20 | 240 mg | 7 | Temples | Face, back | Yes | 90 |
| 11 | 120 | 1800 mg | 75 | Superior/inferior limbs | Face, superior/inferior limbs | Yes | 40 |
| 14 | 30 | 480 mg | 10 | Forehead | Face, neck, chest, back, superior limbs | No | - |
| 15 | 30 | 600 mg | 45 | Superior lip | Face, neck, chest, back, superior/inferior limbs | No | - |
| 17 | 15 | 300 mg | 7 | Temples | Face, neck | Yes | 130 |
| 18 | 14 | 105 mg | 7 | Forehead | Face, back, inferior limbs | Yes | 60 |
| 20 | 40 | 180 mg | 10 | Back | Face, back, inferior limbs | Yes | 60 |
* Latency time from the start of the treatment to the appearance of hypertrichosis. ** Latency time from the end of the treatment to the resolution of hypertrichosis.