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Relative pre-miR-137 and MSH2 mRNA expression in normal (N) and tumor (T) colon tissue from a patient carrying the c*226>G variant in the MSH2 3′UTR. Pre-miR-137 levels were determined by qRT-PCR and normalized to small nucleolar RNA RNU6B. MSH2 mRNA levels were normalized to GAPDH. All data represent the mean ± standard deviation (SD) of 4 independent experiments. Statistical significance was determined by Student’s t-test with a ** p < 0.0001.
