Skip to main content
. 2021 Sep 16;13(9):1484. doi: 10.3390/pharmaceutics13091484

Figure 2.

Figure 2

(a) Expression of transporters on monkey brain endothelial cells using PCR analysis; (b) Expression of efflux transporters ABCB1 and ABCG2 detected by western blot; (c) Functional analysis of ABCB1 using rhodamine 123 (R123) accumulation assay (left) and bi-directional transport of R123 (right). Accumulation of R123 was increased by ABCB1 inhibitor (cyclosporin; 10 μM). Transport of R123 in the basolateral to apical (B-A) was greater than apical to basolateral (A-B). Values presented are means ± SEM (n = 3–4, ** p < 0.01).