Table 3.
Placebo (n = 18) | Kestose (n = 20) | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Baseline | Week 12 | Baseline | Week 12 | ||||||||||||
Relative abundance | |||||||||||||||
Blautia | 0.1665 | ± | 0.0777 | 0.1984 | ± | 0.0800 | 0.1530 | ± | 0.0777 | 0.1281 | ± | 0.0656 | †† | ||
Bifidobacterium | 0.2723 | ± | 0.1201 | 0.1971 | ± | 0.1158 | * | 0.2209 | ± | 0.1762 | 0.3244 | ± | 0.1526 | * | †† |
Sellimonas | 0.0031 | ± | 0.0072 | 0.0044 | ± | 0.0097 | 0.0009 | ± | 0.0022 | 0.0006 | ± | 0.0012 | † | ||
Erysipelatoclostridium | 0.0022 | ± | 0.0030 | 0.0028 | ± | 0.0034 | 0.0007 | ± | 0.0010 | 0.0008 | ± | 0.0014 | † | ||
Megasphaera | 0.0019 | ± | 0.0051 | 0.0025 | ± | 0.0081 | 0.0098 | ± | 0.0281 | 0.0143 | ± | 0.0364 | * | ||
Streptococcus | 0.0414 | ± | 0.0478 | 0.0451 | ± | 0.0654 | 0.0379 | ± | 0.0429 | 0.0183 | ± | 0.0179 | * | ||
Ruminiclostridium 5 | 0.0028 | ± | 0.0044 | 0.0085 | ± | 0.0137 | ** | 0.0091 | ± | 0.0204 | 0.0054 | ± | 0.0119 | ||
Ruminococcaceae UCG-013 | 0.0052 | ± | 0.0088 | 0.0081 | ± | 0.0125 | * | 0.0039 | ± | 0.0046 | 0.0054 | ± | 0.0081 | ||
Lachnospiraceae NK4A136 group | 0.0006 | ± | 0.0014 | 0.0029 | ± | 0.0044 | ** | 0.0040 | ± | 0.0078 | 0.0014 | ± | 0.0023 | ||
Lactobacillus | 0.0034 | ± | 0.0065 | 0.0040 | ± | 0.0088 | 0.0020 | ± | 0.0076 | 0.0142 | ± | 0.0533 | ** | ||
Turicibacter | 0.0035 | ± | 0.0083 | 0.0045 | ± | 0.0122 | 0.0034 | ± | 0.0064 | 0.0017 | ± | 0.0047 | * | ||
Bacillus | 0.0004 | ± | 0.0009 | 0.0095 | ± | 0.0153 | * | 0.0051 | ± | 0.0092 | 0.0038 | ± | 0.0050 | ||
[Ruminococcus] gnavus group | 0.0065 | ± | 0.0132 | 0.0142 | ± | 0.0349 | 0.0149 | ± | 0.0238 | 0.0064 | ± | 0.0084 | ** | ||
Collinsella | 0.0953 | ± | 0.0530 | 0.0796 | ± | 0.0485 | * | 0.0676 | ± | 0.0414 | 0.0792 | ± | 0.0571 | ||
Christensenellaceae R-7 group | 0.0020 | ± | 0.0046 | 0.0045 | ± | 0.0144 | 0.0050 | ± | 0.0130 | 0.0033 | ± | 0.0099 | * | ||
Eggerthella | 0.0031 | ± | 0.0043 | 0.0037 | ± | 0.0043 | 0.0017 | ± | 0.0024 | 0.0011 | ± | 0.0015 |
Data are presented as mean ± SD. * p < 0.05 and ** p < 0.01 vs. Baseline value of the intragroup. † p < 0.05 and †† p < 0.01 vs. placebo value at 12 weeks.