Table 3.
Distribution of the metastatic soft tissue sarcoma patients’ clinical and tumor characteristics.
| Parameter | Extrapulmonary Metastases (n = 28) |
Pulmonary Metastases (n = 90) |
Odds Ratio (95% CI) | p-Value |
|---|---|---|---|---|
| Patient Age (years) b | 57.5 (39.3–67.8) | 59.0 (45.0–69.0) | - | 0.41 d |
| Patient BMI (kg/m2) a | 29.0 ± 7.0 | 30.4 ± 6.8 | - | 0.35 c |
| Largest Tumor Dimension (cm) b | 7.1 (4.6–10.2) | 8.5 (6.0–12.5) | - | 0.12 d |
| Categorical Tumor Size | 0.26 d | |||
| ≤5 cm | 29 (8) | 16 (14) | - | |
| 5–10 cm | 46 (13) | 46 (41) | 0.59 (0.21–1.72) | |
| >10 cm | 25 (7) | 39 (35) | 0.38 (0.12–1.22) | |
| Tumor Location | 0.69 e | |||
| Lower extremity | 54 (15) | 60 (54) | - | |
| Upper extremity | 18 (5) | 14 (13) | 1.41 (0.43–4.58) | |
| Back/torso/neck | 7 (2) | 11 (10) | 0.73 (0.14–3.71) | |
| Pelvis/sacrum | 18 (5) | 9 (8) | 2.29 (0.65 to 8.04) | |
| Acral (hand/foot) | 4 (1) | 6 (5) | 0.73 (0.08 to 6.76) | |
| Tumor Depth | 0.13 e | |||
| Superficial | 18 (5) | 6 (5) | - | |
| Deep | 82 (23) | 94 (85) | 3.04 (0.67 to 13.21) | |
| Tumor Grade | 0.67 d | |||
| Low | 11 (3) | 7 (6) | - | |
| Intermediate | - | 1 (1) | - | |
| High | 89 (25) | 92 (83) | 0.70 (0.17–2.92) | |
| Tumor Margins | 0.26 d | |||
| Positive | 29 (8) | 20 (18) | - | |
| <0.1 cm | 36 (10) | 27 (24) | 0.94 (0.31 to 2.85) | |
| <0.5 cm | 7 (2) | 22 (20) | 0.22 (0.04 to 1.20) | |
| ≥0.5 cm | 29 (8) | 31 (28) | 0.62 (0.20 to 1.95) | |
| Months to metastasis b | 22 (6–45) | 11 (5–19) | - | 0.08 d |
| Months of follow up b | 38 (22–79) | 31 (16–49) | - | 0.50 d |
| Months from first operation until death b | 30 (12–48) | 24 (13–39) | - | 0.31 d |
Data are presented as a mean ± standard deviation for parametric data, b median (IQR) for nonparametric data, or column % (n). p-values: c = ANOVA, d = Kruskal–Wallis test, e = Fisher’s Exact test.