Table 1.
Clinical characteristics of the study patients at baseline.
| Placebo (N = 22) | Iron (N = 44) | |
|---|---|---|
| Anthropometry | ||
| Age, years | 69.2 (5.4) | 66.8 (7.3) |
| Males/females | 16/6 | 26/18 |
| BMI, kg/m2 | 25.1 (2.9) | 24.4 (3.4) |
| FFMI, kg/m2 | 16.14 (1.8) | 15.9 (2.1) |
| Smoking status | ||
| Ex-smoker, N (%) | 13 (59.1) | 20 (45.5) |
| Active, N (%) | 9 (40.9) | 24 (54.5) |
| Packs-year | 56.3 (36.0) | 51.5 (25.8) |
| Pulmonary Function | ||
| FEV1, L | 1.3 (0.3) | 1.4 (0.6) |
| FEV1, % predicted | 47.0 (10.6) | 51.6 (13.5) |
| FVC, L | 3.0 (0.7) | 2.8 (0.8) |
| FVC, % | 84.5 (13.1) | 80.7 (12.6) |
| FEV1/FVC, % | 43.5 (9.1) | 48.7 (10.4) |
| RV, % | 175.9 (40.6) | 176.3 (44.4) |
| RV/TLC, % | 59.3 (7.1) | 60.0 (12.8) |
| TLC, % | 108.5 (15.1) | 110.4 (16.1) |
| DLCO, % | 53.0 (16.7) | 52.3 (12.6) |
| KCO, % | 57.1 (16.2) | 55.0 (12.4) |
| Arterial blood gas | ||
| PaO2, kPa | 10.4 (0.9) | 10.2 (1.1) |
| PaCO2, kPa | 5.1 (0.6) | 5.1 (0.5) |
Data are presented as mean (SD). Abbreviations: BMI, body mass index; FFMI, fat-free mass index; N, number of patients; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; RV, residual volume; TLC, total lung capacity; DLCO, carbon monoxide diffusion capacity corrected for hemoglobin concentration; KCO, Krough transfer factor; PaO2, oxygen partial pressure; PaCO2, carbon dioxide partial pressure.