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. 2021 Sep 9;13(9):3142. doi: 10.3390/nu13093142

Table 2.

Characteristics of included studies.

RQ 1 Publication Study Type
if Applicable: Population
Relevant Findings Level of Evidence 2 Consistency with ESPEN Guideline
1.1 Lacey et al. 2019 [1] Expert opinion
n = 12, experts of varying specialties
  • -

    Plasma osmolality (in mOsm/kg) is an objective surrogate marker of low-intake dehydration

  • -

    Osmolality is underutilized in clinical practice

4 Yes
1.2 Lacey et al. 2019 [1] See above
  • -

    When plasma osmolality cannot be assessed, the authors recommend to calculate plasma osmolarity (CO) (in mmol/L)

4 Yes
Munk et al. 2021
[11]
Diagnostic accuracy study
n = 90, older adults from emergency medical department
  • -

    32% with impending (≥295–300 mOsm/kg) and 11% with current dehydration (>300 mOsm/kg)

  • -

    Significant association between CO and Osmolality

  • -

    Using CO is superior to current clinical practice

2+ Yes
Woijszel et al. 2020
[12]
Cohort study
n = 358, hospitalized older adults
  • -

    58% with dehydration (CO > 295 mmol/L)

  • -

    Dehydration was more frequent in patients with e.g., multimorbidity, polypharmacy, hypertension, diabetes, chronic kidney disease,

2+ Yes
Mantantzis et al. 2020
[13]
Cohort study
n = 1047, community-dwelling older adults
  • -

    33% with dehydration (CO > 296 mmol/L)

  • -

    Higher CO was associated with older age, more morbidities, and greater decline in cognitive functioning and well-being over time

2+ Yes
1.3 Bunn and Hooper 2019
[14]
Diagnostic accuracy study
n = 188, care home residents
  • -

    Commonly used clinical signs and symptoms of low-intake dehydration (49 tested) inadequately discriminated between persons with or without low-intake dehydration

  • -

    The authors suggest to use a 2-stage screening process instead of clinical signs and symptoms

  • -

    1: CO, 2: Serum osmolality measurement if CO > 295 mmol/L

2+ Yes
Lacey et al. 2019
[1]
See above
  • -

    Clinical signs and symptoms are not reliable outside extremes

  • -

    They should not be used alone to detect dehydration

4 Yes
Johnson & Hahn 2018
[15]
Cohort study
n = 60, nursing home residents
  • -

    51% showed renal fluid conservation consistent with dehydration

  • -

    Clinical signs of mucous membranes and tongue furrows did not correlate with serum osmolality

  • -

    Clinical signs might rather reflect physical status and age than dehydration

2− Yes
Akdeniz et al. 2018
[16]
Cohort study
n = 40, hospitalized older adults
  • -

    Average fluid intake was 1747 mL/day

  • -

    20% were dehydrated and 23% had impeding dehydration, despite comparably high fluid intake

  • -

    The clinical relevance of low fluid intake as a marker of dehydration is questionable

2+ Yes
Ekman et al. 2020
[17]
Cohort study
n = 38, rehabilitating older adults after hip surgery
  • -

    Average fluid intake was 1008 mL/day

  • -

    18% with dehydration (≥300 mOsm/kg), those showed correlations to presence of tongue furrows and poor skin turgor

  • -

    21% with concentrated urine, those showed correlations to low fluid intake and a decreased body weight

2− No
2 Cook et al. 2019
[18]
Literature review
care home residents
  • -

    Care home residents have low fluid intake

  • -

    No hydration intervention alone was effective in addressing dehydration

4 Yes
Painter et al. 2017
[6]
Literature review
dementia and aged care facilities
  • -

    Intake of texture-modified fluids was associated with lower energy and fluid intake

  • -

    Lack of evidence that texture modified fluids improve fluid intake and negative consequences (i.e., aspiration, pneumonia)

4 Yes
Jimoh et al. 2019
[19]
Cohort study
n = 22, long-term care residents
  • -

    Drinks are mostly consumed between meals

  • -

    Residents with sufficient fluid intake were offered beverages more frequently and drank more with medications and before breakfast

  • -

    Offering drinks more frequently might improve fluid intake

2- Yes
Marra et al. 2016
[20]
Cohort study
n = 247, long-term-care residents
  • -

    31% with impending (295–300 mOsm/kg) and 38% with dehydration (>300 mOsm/kg)

  • -

    Average water intake was 1147 mL/day

  • -

    Variance in water intake was influenced by, e.g., type of liquid beverage (thin vs. thick), type of ONS, which could be targeted by nutritional interventions

2+ yes
Bak et al. 2018
[21]
Pre-post study
Two wards, nursing home residents
  • -

    Drinking vessels which were lightweight, with large handles and volume of 200–300 mL were preferred

  • -

    Introduction of new vessels at breakfast improved fluid intake

n.a. Yes
Wilson et al. 2019
[22]
Pre-post study
Two care homes, Care home residents
  • -

    Increased choice of beverages and opportunities to drink was associated with increased range of consumed fluid and higher fluid intake

n.a. Yes
3 Masot et al.
[23]
Literature review
Older adults at different care levels
  • -

    Recommendations do not consider physiology of ageing and health problems of older people

  • -

    Authors recommend 1.5–2.0 L of fluid per day

4 Yes
4 Polhuis et al.
[24]
Randomized Trial
n = 20, elderly community-dwelling men
  • -

    The intake of equal volumes of wine and spirits compared to non-alcoholic wine and water resulted in higher urine output within 4 h, but not 24 h

  • -

    Moderate amounts of stronger alcoholic beverages showed short diuretic effects

1++ Yes

1 RQ1: How should low-intake dehydration be identified in older persons? 1.1 by osmolality, 1.2 by osmolarity, 1.3 by clinical signs and bioelectrical impedance (BIA). RQ2: What interventions may help to support older persons to drink well and prevent low-intake dehydration? RQ3: How much should older people drink each day? RQ4: What should older people drink each day? 2 Level of evidence according to the Scottish Intercollegiate Guidelines Network (SIGN) 1++ (highest), 4 (lowest) [4]. SIGN do not have tools for pre-post studies, so for two papers SIGN were not applicable (n.a.). CO = calculated osmolarity, BMI = body mass index, n.a. = not applicable, ONS = oral nutritional supplements, RQ = research question.