Table 1.
ABC transporters identified from Ae. aegypti genome assembly 5 (AaegL5) [25]. (+) = Sense strand; (−) = Antisense strand; Y—Yes, N—No.
| ABC Transporter Gene | VectorBase ID | Chromosome: Physical Location (Strand) | No. of Exons | No. of Transcripts | Protein Length (AA) | Availability of EST (No. of ESTs) | Expression Status in | |
|---|---|---|---|---|---|---|---|---|
| Mosquito Developmental Stages | Arboviral Infection | |||||||
| ABCA Subfamily (11 Genes) | ||||||||
| AaeABCA1 | AAEL012698 | 2:94093797–94103717(−) | 8 | 3 | 1641 | Y (4) | N | Y |
| AaeABCA2.1 | AAEL012702 | 2:94177008–94183151(−) | 11 | 1 | 1636 | Y (26) | N | Y |
| AaeABCA2.2 | AAEL012700 | 2:94160180–94166404(−) | 11 | 1 | 1645 | N | N | Y |
| AaeABCA4 | AAEL001938 | 3:227108694–227135343(+) | 8 | 1 | 1673 | Y (11) | Y | Y |
| AaeABCA5 | AAEL008386 | 3:224734279–224779573(+) | 9 | 2 | 1663 | Y (5) | Y | Y |
| AaeABCA6 | AAEL008384 | 3:224779816–224802105(+) | 10 | 1 | 1657 | Y (1) | Y | Y |
| AaeABCA7.1 | AAEL017572 | 1:117261376–117263613(−) | 2 | 1 | 590 | N | Y | N |
| AaeABCA7.2 | AAEL014699 | 3:51218604–51279389(+) | 7 | 2 | 1635 | Y (18) | Y | Y |
| AaeABCA8 | AAEL021738 | 3:365856244–365899503(+) | 12 | 2 | 1900 | Y (3) | Y | Y |
| AaeABCA9 | AAEL018040 | 3:322613800–322714818(−) | 16 | 2 | 1987 | Y (26) | Y | Y |
| AaeABCA10 | AAEL012701 | 2:94115322–94145067(−) | 8 | 1 | 1622 | Y (6) | N | Y |
| ABCB Subfamily (5 Genes) | ||||||||
| AaeABCB1 | AAEL008134 | 3:107404546–107431730(+) | 5 | 1 | 848 | Y (20) | Y | Y |
| AaeABCB2 | AAEL010379 | 2:182523007–182607302(+) | 11 | 3 | 1307 | Y (2) | Y | Y |
| AaeABCB3 | AAEL022941 | 2:78738879–78757036(−) | 3 | 1 | 725 | Y (10) | Y | Y |
| AaeABCB4 | AAEL006717 | 2:85121437–85146605(+) | 6 | 2 | 820 | Y (9) | Y | Y |
| AaeABCB5 | AAEL000434 | 3:187161644–187197938(+) | 7 | 1 | 693 | Y (8) | Y | Y |
| ABCC Subfamily (16 Genes) | ||||||||
| AaeABCC1 | AAEL005918 | 3:138401412–138418395(−) | 9 | 1 | 1312 | Y (17) | Y | Y |
| AaeABCC2 | AAEL025460 | 3:138444756–138480164(+) | 9 | 4 | 1388 | Y (13) | Y | Y |
| AaeABCC3 | AAEL005929 | 3:138489236–138524582(+) | 11 | 3 | 1419 | Y (7) | Y | Y |
| AaeABCC4.1 | AAEL012395 | 1:284711177–284717415(+) | 5 | 2 | 1357 | Y (9) | N | Y |
| AaeABCC4.2 | AAEL019847 | 1:284693063–284698462(−) | 6 | 1 | 1355 | N | N | Y |
| AaeABCC5 | AAEL023958 | 1:284737104–284863028(+) | 13 | 1 | 1488 | Y (4) | N | Y |
| AaeABCC6 | AAEL027539 | 1:284869084–284903303(+) | 11 | 3 | 1286 | N | N | Y |
| AaeABCC7 | AAEL018267 | 2:100234384–100334146(+) | 7 | 6 | 1394 | Y (23) | Y | Y |
| AaeABCC8 | AAEL005045 | 2:445037808–445059189(−) | 5 | 2 | 1508 | N | Y | Y |
| AaeABCC9 | AAEL005026 | 2:445021476–445037944(+) | 5 | 1 | 1454 | N | Y | Y |
| AaeABCC10 | AAEL005043 | 2:444993656–444999015(+) | 6 | 2 | 1522 | Y (13) | Y | Y |
| AaeABCC12 | AAEL020303 | 2:463313906–463367902(+) | 5 | 1 | 1532 | Y (2) | Y | Y |
| AaeABCC13 | AAEL023524 | 2:312907331–313134735(+) | 25 | 1 | 2101 | Y (1) | Y | Y |
| AaeABCC14 | AAEL004743 | 2:289194273–289251024(+) | 15 | 15 | 1524 | Y (27) | Y | Y |
| AaeABCC16 | AAEL017209 | 3:403021800–403026639(+) | 4 | 1 | 986 | N | Y | N |
| AaeABCC17 | AAEL015644 | 1:193810018–193840226(+) | 9 | 1 | 1339 | Y (10) | Y | Y |
| ABCD Subfamily (2 Genes) | ||||||||
| AaeABCD1 | AAEL010047 | 1:160091832–160259983(+) | 7 | 2 | 753 | Y (14) | Y | Y |
| AaeABCD2 | AAEL002913 | 1:108683838–108734858(+) | 10 | 1 | 659 | Y (27) | Y | Y |
| ABCE Subfamily (1 Gene) | ||||||||
| AaeABCE1 | AAEL010059 | 3:11225514–11239622(+) | 5 | 1 | 609 | Y (66) | Y | Y |
| ABCF Subfamily (3 Genes) | ||||||||
| AaeABCF1 | AAEL001101 | 3:406460452–406484817(−) | 2 | 1 | 894 | Y (16) | Y | Y |
| AaeABCF2 | AAEL010977 | 3:190430154–190451030(+) | 4 | 2 | 602 | Y (97) | Y | Y |
| AaeABCF3 | AAEL010359 | 3:372039893–372056253(+) | 5 | 1 | 712 | Y (52) | Y | Y |
| ABCG Subfamily (18 Genes) | ||||||||
| AaeABCG1 | AAEL016999 | 1:107942728–108005678(−) | 8 | 3 | 716 | Y (17) | Y | N |
| AaeABCG2 | AAEL021570 | 1:30489715–30492114(−) | 4 | 1 | 687 | N | Y | N |
| AaeABCG3 | AAEL008138 | 3:79113447–79286804(−) | 8 | 5 | 862 | Y (15) | Y | Y |
| AaeABCG4 | AAEL003703 | 3:65749828–65763092(−) | 6 | 1 | 616 | Y (1) | Y | Y |
| AaeABCG5 | AAEL017188 | 2:24405169–24438842(+) | 8 | 1 | 614 | N | Y | N |
| AaeABCG7 | AAEL008672 | 2:239556260–239647710(−) | 7 | 2 | 699 | Y (29) | Y | Y |
| AaeABCG8 | AAEL019463 | 2:455430514–455514073(+) | 7 | 1 | 723 | Y (10) | Y | Y |
| AaeABCG10 | AAEL027367 | 2:455272483–455402105(+) | 11 | 7 | 726 | Y (6) | Y | Y |
| AaeABCG11 | AAEL008635 | 2:455184210–455236417(+) | 9 | 1 | 676 | Y (17) | Y | Y |
| AaeABCG13 | AAEL022734 | 1:215452060–215689779(−) | 10 | 5 | 888 | Y (1) | Y | Y |
| AaeABCG14 | AAEL027424 | 1:215707794–215774030(+) | 6 | 1 | 602 | Y (12) | Y | Y |
| AaeABCG15 | AAEL019641 | 2:270847147–271027814(−) | 12 | 3 | 604 | Y (8) | Y | Y |
| AaeABCG16 | AAEL008625 | 2:455514069–455540158(−) | 5 | 1 | 606 | N | Y | Y |
| AaeABCG17 | AAEL008628 | 2:455557594–455572391(+) | 6 | 2 | 598 | N | Y | Y |
| AaeABCG18 | AAEL008632 | 2:455591457–455609699(+) | 6 | 3 | 607 | Y (4) | Y | Y |
| AaeABCG19/ G20 | AAEL026976 | 2:455663955–455680847(+) | 7 | 3 | 599 | N | Y | Y |
| AaeABCG21 | AAEL008624 | 2:455615233–455650540(+) | 6 | 5 | 593 | Y (6) | Y | Y |
| AaeABCG22 | AAEL027686 | 3:223544987–223689078(−) | 8 | 1 | 612 | Y (12) | Y | Y |
| ABCH Subfamily (3 Genes) | ||||||||
| AaeABCH1 | AAEL005491 | 3:59371559–59533418(+) | 8 | 5 | 814 | Y (1) | Y | Y |
| AaeABCH2 | AAEL018334 | 1:181178199–181420930(+) | 11 | 5 | 814 | Y (3) | Y | Y |
| AaeABCH3 | AAEL014428 | 1:159149149–159331370(−) | 12 | 3 | 727 | Y (1) | Y | Y |