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. 2021 Aug 25;14(9):843. doi: 10.3390/ph14090843

Table 2.

Diagnostic accuracy of suPAR, NGAL and the combination of both biomarkers, using optimal cut-off values, for predicting AKI.

Cutoff Sensitivity Specificity PPV NPV AUC (CI 95%)
suPAR (ng/mL) 4.26 0.94 0.40 0.15 0.98 0.69 (0.60–0.77)
NGAL (ng/mL) 139.5 0.76 0.67 0.20 0.96 0.78 (0.70–0.87)
Two-variable interaction - 0.82 0.73 0.25 0.97 0.82 (0.73–0.90)

Two-variable interaction, includes interaction between suPAR and NGAL.