Figure 6.

Shows representative TrkB and GAD65 immunofluorescent staining in the VCx (layers I-IV) of rats. Representative TrkB (red) and GAD65 (green) immunofluorescent staining in the contralateral visual cortex of coronal brain sections from ONC+rhNGF or ONC rats. A weak TrkB expression is evident in a minor number of cell bodies and in neuronal varicosities, while a widespread GAD65 staining is present in the ONC VCx. Upon rhNGF treatment, TrkB positive cell soma and neuronal endings are strongly enhanced. Please, note the GAD65 immunoreactive afferents surrounding most of the TrkB positive cell soma in the ONC+rhNGF VCx (inlet, dotted lines). (Scale bars: 200 mm; inlet: 50 mm).