Table 1.
Relative logarithmic expression (RLE) of P2XRs in MCs, astrocytes, and oligodendrocytes. P2XR RLE expression in skin MCs [142], cerebellum and cortex astrocyte and oligodendrocyte precursors [143] was obtained using Fantom 5 and compared to cell types with the highest RLE for a given receptor.
Gene | MCs | Astrocytes | Oligodendrocytes | Cell Types/Tissues with Highest RLE | |
---|---|---|---|---|---|
Skin (n = 4) | Cerebellum (n = 3) | Cortex (n = 3) | Precursors (n = 1) | ||
P2X1 | 337.186 | 3.017 | 3.345 | 1.692 | 337.186 (MCs) |
P2X2 | 0.032 | 0 | 0 | 0 | 15.242 (Seminal vesicle) |
P2X3 | 25.120 | 67.947 | 96.481 | 51.310 | 282.548 (Smooth muscle cells) |
P2X4 | 27.792 | 6.232 | 4.140 | 6.202 | 679.838(CD14+ monocytes) |
P2X5 | 71.924 | 363.640 | 0.814 | 294.329 | 2237.838 (Bronchial epithelial cells) |
P2X6 | 2.373 | 1.187 | 65.063 | 0 | 25.101(Cerebellum) |
P2X7 | 14.628 | 0.164 | 0.324 | 0.564 | 692.939 (CD14+ monocytes) |