Table 1.
Association of TRIM66 rs112369934 in quantitative phenotypes.
| Phenotype | Wildtype TT | Variant TC | Mean Difference (95% CI) | p-Value | ||
|---|---|---|---|---|---|---|
| N Eyes | Mean (SD) | N Eyes | Mean (SD) | |||
| MD (dB) | 3400 | −8.36 (9.02) | 457 | −8.64 (9.04) | 0.27 (−0.81 to 1.36) | 0.62 |
| PSD (dB) | 3403 | 5.20 (3.47) | 457 | 5.27 (3.40) | −0.07 (−0.45 to 0.32) | 0.73 |
| CCT | 3961 | 533.84 (40.07) | 578 | 529.61 (36.46) | 4.23 (−0.09 to 8.55) | 0.055 |
| CDR | 3986 | 0.71 (0.17) | 569 | 0.72 (0.17) | −0.02 (−0.03 to 0.00) | 0.12 |
| IOP | 4241 | 17.32 (6.00) | 617 | 17.67 (6.66) | −0.35 (−1.06 to 0.35) | 0.33 |
| VA.CC | 3653 | 0.38 (0.84) | 522 | 0.46 (0.92) | −0.08 (−0.17 to 0.01) | 0.09 |
| VA.SC | 2791 | 0.57 (0.98) | 374 | 0.69 (1.12) | −0.12 (−0.26 to 0.02) | 0.09 |
| RNFL | 3401 | 73.40 (14.98) | 475 | 72.29 (15.50) | 1.12 (−0.73 to 2.96) | 0.24 |
Mean deviation (MD), pattern standard deviation (PSD), central corneal thickness (CCT), cup-to-disc ratio (CDR), intra-ocular pressure (IOP), visual acuity (VA) with correction (CC) and without correction (SC), retinal nerve fiber layer (RNFL).