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. 2021 Aug 26;10(9):1359. doi: 10.3390/antiox10091359

Table 3.

Average concentrations of leached metal ions from orthodontic appliances.

Metal Ion Release from Orthodontic Appliances
Fe Ni Cr Ti Mo Co Alloy Type Time Ref.
310 ± 123.1 ppb 1292 ± 437.5 ppb 0 ppb / / 4 ± 5.477 ppb SS wire + SS brackets + SS band 90 days [106]
450 ± 222.8 ppb 1864 ± 600.2 ppb 18 ± 34.9 ppb / / 10 ± 7.071 ppb NiTi wire + SS brackets + SS band
614 ± 531.7 ppb 2466 ± 867.8 ppb 30 ± 51.9 ppb / / 12 ± 4.47 ppb Co-NiTi wire + SS brackets + SS band
534 ± 558 ppb 2132 ± 1143 ppb 20 ± 44.72 ppb / / 12 ± 4.472 ppb Elgiloy wire + SS brackets + SS band
2382 ppb 573 ppb 101 ppb / / / SS wires, SS brackets, SS bands, SS metal ligatures 30 days [34]
1107 ppb 15 ppb 8 ppb / / / control
/ 18.5 ± 13.1 ppb 2.6 ± 1.6 ppb / / / SS brackets and bands; SS + NiTi archwires 16 ± 2 months [29]
/ 11.9 ± 11.4 ppb 2.2 ± 1.8 ppb / / / control
10.78 ± 17.66 µg 28.33 ± 29.19 µg 12.66 ± 4.61 µg / 133.33 ± 57.7 µg / NiTi archwire + Dentaurum brackets 28 days [107]
21.33 ± 8.73 µg 17.66 ± 11/59 µg <10 ± 0 µg / 110 ± 17.32 µg / NiTi archwire + American Ortho brackets
14.33 ± 5.33 µg 76.66 ± 62.52 µg 16.66 ± 11.54 µg / <130 ± 0 µg / NiTi archwire + Shinye brackets
<10 ± 0 µg 22 ± 7.54 µg 30 ± 0 µg / 120 ± 17.32 µg / NiTi archwire + ORJ brackets
16 ± 5.29 µg 37 ± 20.042 µg 26 ± 6.92 µg / 110 ± 17.32 µg / SS archwire + Dentaurum brackets
11 ± 1.73 µg 45 ± 31 µg 26 ± 6.92 µg / 0 ± <100 µg / SS archwire + American Ortho brackets
<10 ± 0 µg 293.2 ± 365.6 µg 15.33 ± 4.61 µg / 0 ± <100 µg / SS archwire + Shinye brackets
<10 ± 0 µg 44.66 ± 35.50 µg 15.33 ± 4.61 µg / 110 ± 17.32 µg / SS archwire + ORJ brackets
67.7 ± 9.6 ppb 10 ± 6.3 ppb 4.5 ± 0.5 ppb 2 ± 0.6 ppb / / NiTi New brackets + new archwire 45 days [41]
64.3 ± 8 ppb 15 ± 3.3 ppb 4 ± 0.7 ppb 2 ± 0.7 ppb / / NiTi Recycled brackets + new archwire
115 ± 11.9 ppb 20 ± 6.5 ppb 7.3 ± 0.6 ppb 3.5 ± 1.3 ppb / / NiTi New brackets + recycled archwire
140 ± 9.4 ppb 20 ± 3.3 ppb 7.5 ± 0,6 ppb 4 ± 0.7 ppb / / NiTi Recycled brackets + recycled archwire
/ 2 ppb / / / / NiTi archwire 28 days [108]
/ / / / / / TMO archwire
289 ppb 6 ppb 11 ppb / / / SS archwire
/ 4 ppb 3 ppb / / / Cu-NiTi archwire
/ 67 ± 10.8 ppb 30.8 ± 4.3 ppb / / / SS brackets, bands NiTi & SS archwires 1.5 years [31]
/ 5.02 ± 0.001 ppb 1.27 ± 0.09 ppb / / / control
/ 0.93 ± 0.04 μg / / / / NiTi archwires 21 days [35]
/ 0.66 ± 0.02 μg / / / / SS archwires
/ 0.67 ± 0.02 μg / / / / CuNiTi archwires
/ 0.77 ± 0.05 μg / / / / Ion implanted NiTi archwires
/ 125 ± 22 μg 112 ± 18 μg / / / SS ¼ archwire + bands + brackets 12 days [40]
96.06 ± 57.4 ppb/day 41.66 ± 33.99 ppb/day 33.43 ± 24.05 ppb/day 0 ± 0 / / SS archwire 1st day [38]
25.55 ± 10.00 ppb/day 10.21 ± 2.68 ppb/day 3.83 ± 1.93 ppb/day 0 ± 0 / / 6th day
11.08 ± 5.89 ppb/day 5.28 ± 1.87 ppb/day 1.43 ± 0.69 ppb/day 0 ± 0 / / 7th day
5.62 ± 1.47 ppb/day 3.84 ± 0.86 ppb/day 0.70 ± 0.10 ppb/day 0 ± 0 / / 14th day
38.47 ± 15.67 ppb/day 11.77 ± 2.84 ppb/day 10.49 ± 3.90 ppb/day 0.14 ± 0.04 ppb/day / / NiTi archwire 1st day [38]
26.93 ± 5.44 ppb/day 10.83 ± 3.49 ppb/day 3.30 ± 0.95 ppb/day 0.01 ± 0 ppb/day / / 6th day
13.07 ± 4.01 ppb/day 6.13 ± 1.39 ppb/day 1.76 ± 0.34 ppb/day 0.01 ± 0.01 ppb/day / / 7th day
6.81 ± 1.70 ppb/day 3.38 ± 1.67 ppb/day 1.06 ± 0.21 ppb/day 0.01 ± 0 ppb/day / / 14th day
21.18 ± 6,43 ppb/day 7.12 ± 1.33 ppb/day 4.39 ± 1.99 ppb/day 0.12 ± 0.02 ppb/day / / Termo NiTi archwire 1st day [38]
19.11 ± 6.28 ppb/day 7.26 ± 1.10 ppb/day 2.10 ± 0.84 ppb/day 0.01 ± 0 ppb/day / / 6th day
8.79 ± 3.79 ppb/day 5.06 ± 1.57 ppb/day 1.23 ± 0.80 ppb/day 0.01 ± 0 ppb/day / / 7th day
2.50 ± 0.59 ppb/day 2.33 ± 0.77 ppb/day 0.40 ± 0.15 ppb/day 0 ± 0 / / 14th day
42.33 ± 27.06 ppb 0.00 ± 0.00 ppb 0.36 ± 0.33 ppb 6.64 ± 2.00 ppb 0.80 ± 0.27 ppb 0.00 ± 0.00 ppb control 30 days [25]
520.0 ± 210.1 ppb 416.9 ± 133.5 ppb 8.97 ± 6.73 ppb 9.03 ± 2.08 ppb 3.11 ± 1.47 ppb 1.38 ± 1.25 ppb SS brackets + SS bands
49.67 ± 29.29 ppb 0.00 ± 0.00 ppb 0.06 ± 0.05 ppb 5.35 ± 3.96 ppb 0.11 ± 0.07 ppb 0.03 ± 0.01 ppb Ti brackets + Ti bands
179.49 ± 99.1 ppb 5.79 ± 2.07 ppb 0.91 ± 0.28 ppb 3.79 ± 3.11 ppb 0.60 ± 0.21 ppb 0.00 ± 0.00 ppb Ni-free brackets + bands