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. 2021 Aug 24;9(9):942. doi: 10.3390/vaccines9090942

Table 3.

Univariate and multivariable logistic regression analyses of risk factors associated with vaccine hesitancy (Yes vs. No, No as reference).

Survey Question Univariate a Multivariable b
E/N OR (95% CI) p E/N OR (95% CI) p
What is your age? <0.001 c 0.358 c
 18–29 years old 72/216 Reference 60/185 Reference
 30–59 years old 46/215 0.547 (0.354, 0.838) 0.005 38/193 0.625 (0.251, 1.524) 0.302
 60+ years old 7/82 0.198 (0.082, 0.417) <0.001 5/75 0.371 (0.090, 1.400) 0.145
Which gender do you identify with?
 Female 76/238 Reference 62/206 Reference
 Male 48/271 0.461 (0.304, 0.694) <0.001 41/247 0.963 (0.557, 1.669) 0.893
What is your marital status? 0.003 c 0.227 c
 Single 69/230 Reference 55/196 Reference
 Married 46/261 0.501 (0.327, 0.764) 0.001 42/239 1.939 (0.861, 4.485) 0.111
 Divorced/separated/widowed 7/19 1.394 (0.516, 3.536) 0.498 6/18 2.794 (0.628, 11.841) 0.174
What country were you born in?
 North Africa/Middle East 53/275 Reference 42/251 Reference
 North America/Europe 71/229 1.876 (1.249, 2.832) 0.002 61/202 0.999 (0.267, 3.390) 0.998
When did you move to the United States? <0.001 c 0.910 c
 Less than 10 years 22/76 Reference 18/65 Reference
 20 years ago or longer 32/218 0.422 (0.228, 0.788) 0.007 25/196 0.855 (0.342, 2.168) 0.740
 Born in the United States 70/218 1.150 (0.658, 2.055) 0.628 60/192 1.120 (0.325, 4.434) 0.863
What is your highest level of education? If currently enrolled, please note your highest degree received.
 No professional degree 91/233 Reference 73/191 Reference
 Professional degree 34/279 0.219 (0.139, 0.338) <0.001 30/262 0.543 (0.270, 1.073) 0.079
What kind of health care professional are you? <0.001 c 0.049 c
 Physician/Nursing 28/250 Reference 26/238 Reference
 Allied profession 47/93 7.975 (4.585, 14.140) <0.001 44/88 2.434 (1.117, 5.319) 0.025
 Student 38/141 2.904 (1.703, 5.007) <0.001 33/127 1.320 (0.527, 3.366) 0.554
What is your yearly household income?
 Under $150,000 90/242 Reference 77/213 Reference
 Over $150,000 30/260 0.223 (0.139, 0.349) <0.001 26/240 0.455 (0.243, 0.838) 0.011
Have you received an influenza vaccine in the last 5 years?
 Yes 77/443 Reference 66/403 Reference
 No 42/57 12.967 (7.037, 25.044) <0.001 37/50 8.896 (4.315, 19.252) <0.001
I know someone personally who has contracted COVID-19.
 Yes 112/486 Reference 94/433 Reference
 No 13/27 3.099 (1.419, 6.730) 0.005 9/20 1.895 (0.580, 5.874) 0.282
I know someone personally who has died of COVID-19.
 No 64/219 Reference 53/196 Reference
 Yes 61/293 0.638 (0.425, 0.955) 0.029 50/257 0.977 (0.556, 1.717) 0.934

COVID-19, coronavirus disease 2019; E/N, numbers of events and participants; OR, odds ratio. Bold and italic is used to emphasize statistical significance (p ≤ 0.005). a Univariable logistic regression analysis. b Multivariable logistic regression analysis. c Global p-value obtained by likelihood ratio tests.