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Effect of co-application and pretreatment of IMI on nicotine-evoked current amplitudes. (A) Currents induced by 10 mM nicotine (NIC) and the co-application of both 10 µM imidacloprid and 10 mM nicotine. (B) Histograms illustrating co-application of 10 µM imidacloprid (IMI) with 10 mM nicotine. (C,D) currents and histograms under 10 mM nicotine and 5 min pretreatment with 10 µM imidacloprid (IMI). Data are mean ± SEM. * p < 0.05. Each histogram represents n = 12.
