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. 2021 Aug 24;12(9):1296. doi: 10.3390/genes12091296

Figure 3.

Figure 3

The potential role of selected lncRNAs in the course of SSc pathogenesis. ALK1, activin receptor-like kinase 1; COL1, type I collagen; CXCL10, C-X-C motif chemokine ligand 10; CXCL11, C-X-C motif chemokine ligand 10; EGF, epidermal growth factor; EZH2, enhancer of zeste homolog 2; HOTAIR, HOX transcript antisense RNA; IFN, interferon; LSD1, lysine-specific histone demethylase 1A; MAPK, p38 mitogen-activated protein kinase; mTOR, mammalian target of rapamycin; PI3K, class I phosphoinositide 3-kinase; RhoA, Ras homolog family member A; S1P1, sphingosine 1 phosphate receptor 1; TGF-β, tumor necrosis factor-beta; TLRs, Toll-like receptors.