Figure 5.

Gene expression (left) and protein abundance (right) of UGTs in hepatic tissues from hepatitis C (HCV, n = 21), primary biliary cholangitis (PBC, n = 10), primary sclerosing cholangitis (PSC, n = 6), alcoholic liver disease (ALD, n = 20) and autoimmune hepatitis (AIH, n = 20) patients and the controls (n = 20). The data are represented as box-plots of the median (horizontal line), 75th (top of box), and 25th (bottom of box) quartiles, the smallest and largest values (whiskers) and mean (+) are shown. mRNA levels of the analyzed genes were expressed as relative amounts to the mean of five housekeeping genes (GAPDH, HMBS, PPIA, RPLP0, RPS9). Statistically significant differences: * p < 0.05, ** p < 0.01 (Kruskal–Wallis test post hoc Dunn’s test with Bonferroni correction) in comparison to the controls.