Table 1.
Summary of data obtained from the 16 found articles.
| Authors | Number of Cases | Age | M:F | Cardiac Death |
Cardiac Infection |
Macroscopic | Microscopic | IHC | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Weight | Ventricular Dilatation/ Myocyte Hypertrophy |
Necrosis | Lymphocytic Infiltration Parenchyma |
Microthrombi/ Cardiac Vessels Involvement |
||||||||
| Lindner et al. 2020 [15] |
39 | 85 (78–89) | 16:23 | 1 Prior HF, 38 ARDS | 15 (+) interstitial cells within the cardiac tissue |
Not reported | None | None | 0 | - | Yes | |
| Fox et al. 2020 [16] |
22 | 68.5 (44–79) | 10:12 | 0 | 16 | 340 to 1010 g | 9 RVD Se R:L >1:1 Right Hypertrophy |
Individual cell dropout/necrosis/apoptosis | 0 | - | Yes | |
| Jacobs et al., 2020 [17] | 1 | 48 | 1 | 1 Fulminant Myocarditis due to COVID-19 |
1 | 605 | 1 | piecemeal necrosis | 1 | - | Yes | |
| Pellegrini et al. 2020 [19] |
40 | 74 | 29:11 | 3 HF, 37 RF | 8 | Not reported | Not reported | 14 (3 infarction, 11 focal necrosis) | 9 | 9 | No | |
| Gauchotte et al. 2021 [20] |
1 | 69 | 1 | 1 Fulminant myocarditis due to COVID-19 | 1 | 403 | none | None | 1 | - | Yes | |
| Bulfamante et al., 2020 [21] | 6 | 59.5 (54–69) | 1:5 | 6 RF | 6 | 410–750 | 1 LVH (prior), 6 RVD (lung overload) | 6 | 6 | - | Yes | |
| Del Nonno et al., 2020 [22] | 9 | 70 (35–92) | 7:2 | 9 (6 shock, 3 sudden death) | 0 | 450 | No supplementary available | 9 | 9 | 9 | No | |
| Basso et al. 2020 [23] |
21 | 69 (44–86) | 15:6 | 1 HF, 1 Sudden death, 19 RF | Not reported | Not reported | Not reported | 4 | 3 criteria /11 infiltration |
3 | Yes | |
| Hanley et al. 2020 [24] |
10 | 73 (52–79) | 6:3 | 9 RF | 2 | 450 (312–513) | 4 LVH | 1 | 0 | 6 | No | |
| Rapkiewicz et al., 2020 [25] | 7 | 57 (44–65) | 3:4 | 7 RF | Not reported | Not Reported | Not reported | 3 | 1 | 7 | No | |
| Cîrstea et al., 2020 [26] | 1 | 30 | 0:1 | 1 HF | Not reported | Not reported | Not reported | 0 | 1 | 1 | No |
|
| Bradley et al., 2020 [27] | 14 | 73.5 (42–84) | 6:8 | 1 VF, 1 LVF, prior 12 RF |
0 | Not reported | 13 CH | 1 | 1 | 0 | No | |
| Duarte-Neto et al., 2020 [30] | 10 | 69 (33–83) | 5:5 | 10 RF | Not reported | Not reported | 9 CH | 0 | 2 | 2 | No | |
| Schaller et al., 2020 [32] | 10 | 69 (64–90) | 7:4 | Not reported | Not reported | Not reported | Not reported | Not reported | 4 | 0 | No | |
| Buja et al., 2020 [33] | 3 | 48 (34–62) | 3:0 | 2RF, 1 SD | Not reported | 720 (420–1070) | 2CH | 0 | 2 | 0 | No | |
| Bois et al., 2021 [34] | 15 | 78 (71–86) | 12:3 | Not reported | 5 | 443.1 (286.3–545.0) | Not reported | 9 | 5 | 12 | Yes | |
HF—Heart Failure; RF—Respiratory failure; CH—Cardiac Hypertrophy; LVH—Left Ventricular Hypertrophy; RVD—Right Ventricular Disfunction; IHC—immunohistochemistry.