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. 2021 Sep 10;8(9):190. doi: 10.3390/vetsci8090190

Figure 7.

Figure 7

Pregnancy rates (A) and pregnancy losses (B) up to 60 days of cyclic and acyclic mares synchronized with long-acting progesterone (LAP4) or intravaginal progesterone-releasing device for the first time (IPRD, n = 130) or resynchronized with IPRD (n = 32) between 8 and 15 days after the first synchronization (RE-IPRD). Cyclic (n = 75): mares having ovulation confirmed after induction of ovulation (follicle ≥ 35 mm) with histrelin acetate (250 µg); LAP4 (n = 92): acyclic mares treated with estradiol-17β for 3 days and then administered a single dose of long-action progesterone (LAP4, 1.5 g); IPRD (n = 130): acyclic mares treated with estradiol-17β for 3 days and then given an IPRD containing 1 g of natural progesterone; RE-IPRD: mares not used after 8 days after insertion of an IPRD in the first synchronization were treated 8–15 days later with estradiol-17β for 3 days and then given a new IPRD. Embryo transfer was performed 4–8 days after ovulation or progesterone treatment and pregnancy diagnosis was performed 5 days later. Once pregnancy was confirmed, mares in the 3 acyclic groups received weekly injections of LAP4 (1.5 g) until 120 days of pregnancy. Mares in IPRD and RE-IPRD groups had the device removed three days after the first PD.