Table 1.
Summary of the review publications issued in recent years [1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31].
| Authors | Title | Aim |
|---|---|---|
| Uday B Kompella et al., 2010 [2] |
Recent advances in ophthalmic drug delivery | Updates of the noninvasive sustained ophthalmic drug delivery systems administered at the front of the eye (mucoadhesives, viscous polymer vehicles, transporter-targeted prodrug design, receptor-targeted functionalised nanoparticles, iontophoresis, punctual plug). |
| Gourishanker Jha, Amit Kumar 2011 [6] |
Drug delivery through soft contact lenses: An introduction | Methods of preparing polymer hydrogels CLs (contact lenses) loaded by ophthalmic drugs. |
| Rituraj Shivhare 2012 [7] |
An updated review on novel advanced ocular drug delivery system | Modern drug delivery systems: inserts, contact lenses, mucoadhesive, collagen shield, penetration enhancers, implants, particulate; vascular system like liposomes, niosomes, pharmacosomes, microemulsion, nanoparticles, iontophoresis, dendrimers; and gene therapy, aptamers, protein and peptide therapy, oligonucleotide, siRNA, stem cell therapy. |
| Kumar Manish et al., 2012 [8] |
Recent advances in ophthalmic drug delivery system | The update on ocular drug delivery systems. Selection of polymeric drug carriers, methods of drug complexation with particular attention to in vivo studies. |
| Hitesh Gohel et al., 2012 [9] |
Drug-Eluting Therapeutic Contact Lens |
The potential of therapeutic lenses as an effective formulation for ophthalmic drug delivery. |
| Ana Guzman-Aranguez et al., 2013 [10] |
Lenses: Promising Devices for Ocular Drug Delivery |
Current techniques for the delivery of ophthalmic drugs by CLs. The pros and cons. |
| Djamila Achouri et al., 2013 [11] |
Recent advances in ocular drug delivery |
The update on ocular dosage formulas. Chemical delivery systems: prodrugs, cyclodextrins. Drug delivery systems: polymeric gels, bioadhesive hydrogels, in-situ forming gels with temperature-, pH-, or osmotically induced gelation, a combination of polymers, and colloidal systems: liposomes, niosomes, cubosomes, microemulsions, nanoemulsions, and nanoparticles. |
| Peter WJ Morrison et al., 2014 [12] |
Advances in ophthalmic drug delivery |
Strategies for ocular drug delivery from basic formulation techniques to improvements with viscosity enhancers and mucoadhesives. |
| R. Kumar Sharma, et al., 2014 [13] |
Nanostructure-based platforms-current prospective in ophthalmic drug delivery | Insights into a novel approach: hydrophilic nanogels, solid lipid nanoparticles, and nanosponges for insoluble in water drugs. |
| Chau-Minh Phan et al., 2017 [14] |
Contact lenses for antifungal ocular drug delivery: a review | Delivery of antifungal drugs by CLs. Main factors influencing the effectiveness of drug delivery through CLs. |
| Maulvi, FA et al., 2016 [15] |
A review on therapeutic contact lenses for ocular drug delivery | Methodologies to develop therapeutic contact lenses. Advantages and limitations. |
| Helena Prior Filipe et al., 2016 [5] |
Contact lenses as drug-controlled release systems: a narrative review | Strategies to enhance drug residence time and bioavailability. Clinical applications of drug-soaked CLs as DCRS (drug controlled release system) combined with delivery diffusion barriers, incorporation of functional monomers, ion-related controlled release, molecular imprinting, nanoparticles, and layering. |
| Alex Hui 2017 [16] |
Contact lenses for ophthalmic drug delivery | In-vitro experiments in the context of the drug-soaked CLs treatment: infectious, inflammatory, allergic, and glaucomatous diseases. Vitamin E diffusion barriers, modified ionicity, molecular imprinting, and incorporation of drug reservoirs. |
| Md. Kabir Imtiazul 2017 [3] |
Emerging Trends in Ocular Drug Delivery: A Review on Recent Updates | An overview of drug delivery devices: Novasorb®, Cationform®, Sothe®, Lipimix®, Tear again®, Durasite®, Durasert™, Anterior microPump™, Posterior MicroPump™, Eye link™ and drug refill system™, Cortiject®. |
| Jervis LP 2017 [17] |
A Summary of Recent Advances in Ocular Inserts and Implants |
Latest developments in ocular delivery using ocular implants and inserts. |
| Yerikala Ramesh et al., 2017 [18] |
Novel approaches on ocular drug delivery system | Novel drug delivery dosage forms: nanoparticles, liposome, ocuserts, and mucoadhesive formulations. |
| Seung Woo and Jaeyun Kim 2018 [19] |
Therapeutic Contact Lenses with Polymeric Vehicles for Ocular Drug Delivery: A Review | Overall trends in methodology to develop therapeutic contact lenses with polymeric vehicles. |
| Jaimini Gandhi 2018 [20] |
A Review on Current Perspectives and Recent Advances in Ocular Drug Delivery System | Novel ophthalmic delivery systems: ocular inserts, collagen shields, ocular films, disposable contact lens, niosomes 20 and nanoparticles. |
| Eliana B. Souto et al., 2019 [21] |
Review Advanced Formulation Approaches for Ocular Drug Delivery: State-Of-The-Art and Recent Patents |
Advanced formulations for ophthalmic delivery: nano-enhanced CLs, dendrimers, intraocular implants, in situ gelling nanosystems, liposomes, nanomicelles, nanoparticles, nanosuspensions, microneedles technologies. |
| Vrinda Gote et al., 2019 [1] |
Ocular Drug Delivery: Present Innovations and Future Challenges | Novel drug-delivery technologies: nanoparticles, nanomicelles, dendrimers, microneedles, liposomes, and nanowafers, are increasingly studied for anterior and posterior disorders. |
| Arpita Bhattacharjee et al., 2019 [22] |
Novel drug delivery systems for ocular therapy: With particular reference to liposomal ocular delivery | Current research in ocular delivery of drugs with particular emphasis on the liposomal delivery system. |
| Yumei Wu et al., 2019 [23] |
Research progress of in-situ gelling ophthalmic drug delivery system |
An in-situ gelling in the ocular drug delivery systems. |
| Carmen Alvarez-Lorenzo et al., 2019 [24] |
Bioinspired hydrogels for drug-eluting contact lenses | Bioinspired drug-imprinted CLs, CLs for macromolecules ingredients, CLs for stimulus-responsive release and others. |
| Sonia Dhiman et al., 2020 [25] |
Recent Advances in Nano-Formulations for Ophthalmic Drug Delivery | Nanoparticles eye drops in ocular drug delivery—microemulsions, nanosuspospensions, nanoparticles, liposomes, niosomes, dendrimers, cyclodextrins, nanoshells, superparamagnetic nanoparticles. |
| Courtney R. Lynch et al., 2020 [26] |
Hydrogel Biomaterials for Application in Ocular Drug Delivery |
Biopolymers in the formulation of ocular hydrogel systems: chitosan, hyaluronic acid, gelatin, alginate, methylcellulose, collagen. |
| M.A. Holgado et al., 2020 [4] |
Contact lenses as drug-delivery systems: a promising therapeutic tool Lentes de contacto para vehiculizar principios activos: una prometedora herramienta terapéutica |
Examples of medications applied to the therapeutic contact lenses: antibiotics, corticoids, anti-inflammatories, immunosuppressants and others. |
| Gary D. Novack et al., 2020 [27] |
Ocular Drug Delivery Systems UsingContact Lenses | The challenges with current therapies, pharmacokinetics, and pharmacodynamics of different drug classes and the patient population. |
| Assumpta Peral et al., 2020 [28] |
Contact Lenses as Drug Delivery System for Glaucoma: A Review | Contact lenses as drug delivery system in glaucoma treatment. |
| Olivia L. Lanier et al., 2021 [29] |
Review of Approaches for Increasing Ophthalmic Bioavailability for Eye Drop Formulations |
Methods of improving eye drop formulations comprising the addition of viscosity enhancers, permeability enhancers, mucoadhesives, vasoconstrictors, or puncta occlusion, nanocarriers, or prodrugs. |
| Zhiguo Li et al., 2021 [30] |
Recent Advances in New Copolymer Hydrogel-Formed Contact Lenses for Ophthalmic Drug Delivery |
Material components used in the context of CLs: pHEMA, MAA, DMA, NVP, EGDMA, TRIS and PDMS. Pros and cons of each material in constructing a drug release device. |
| Paola Franco et al., 2021 [31] |
Contact Lenses as Ophthalmic Drug Delivery Systems: A Review | An updated overview of the latest developments and future perspectives in the methodology of manufacturing and using therapeutic contact lenses. |
pHEMA: poly-2-hydroxyethyl methacrylate, MAA: methyl methacrylate, DMA: dimethylacetamide, NVP: N-vinyl pyrrolidone, EGDMA: ethylene glycol dimethacrylate TRIS: tris(trimethyl siloxy) silyl-propyl methacrylate, PDMS: polydimethylsiloxane.