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. 2021 Sep 7;22(18):9689. doi: 10.3390/ijms22189689

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Common journey of neural cells through ischemic brain injury and Alzheimer’s disease. Despite diverse genetic predispositions, cerebral ischemia and Alzheimer’s disease (AD) share common risk factors and pathophysiological processes and mechanisms, all leading to cell death. For more information, please refer to the main text and the publications indicated by the reference numbers in square brackets. Abbreviations: ApoE, apolipoprotein E; APP, amyloid precursor protein; CNS, central nervous system; PSEN1/2, presenilin 1/2.