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Caveolae and caveola-related domains. A diagram summarizing the various biochemical, morphological, and functional features of these plasma membrane-associated microdomains is shown. See text for details. DIGs, detergent-insoluble glycolipid-rich membranes; GEMs, glycolipid-enriched membranes; GPCRs, G-protein-coupled receptors; RTKs, receptor tyrosine kinases; NRTKs, nonreceptor tyrosine kinases; PLDs, phospholipase D.
