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. 2021 Sep 18;22(18):10107. doi: 10.3390/ijms221810107

Figure 1.

Figure 1

Inhibition of BMI-1 decreases the cancer cell stem-like cell population: (A) Caki and HeLa cells were treated with BMI-1 inhibitor PTC596 (5 nM) for 12 h; (B) Caki and HeLa cells were transfected with Control (Cont) or BMI-1 siRNA for 24 h. The population of stem-like cells was detected by flow cytometry and the protein expression was quantified by Western blotting (B); (C): The CD44 cancer stem cell marker was analyzed by flow cytometry in PTC596-treated Caki and HeLa cells. * p < 0.05 compared to the control.