Table 1.
Baseline features of the overall population, and differences between the ischemic groups (G1 and G2) and control group (G3).
| Overall Population (N = 362) |
G1/G2 (N = 272) |
G3 (N = 90) |
p-Value | |
|---|---|---|---|---|
| age (years) | 64 ± 13 | 66 ± 12 | 59 ± 14 | <0.001 |
| male gender | 245 | 199 | 46 | <0.001 |
| BMI (kg/m2) | 25.9 ± 3.4 | 26.0 ± 2.9 | 25.5 ± 4.7 | 0.33 |
| arterial hypertension | 242 | 201 | 41 | <0.001 |
| diabetes mellitus | 87 | 74 | 13 | 0.01 |
| dyslipidemia | 188 | 150 | 38 | 0.03 |
| smoking habit | 142 | 114 | 28 | 0.07 |
| familial history of CV disease | 134 | 113 | 21 | 0.001 |
| AF | 44 | 35 | 9 | 0.47 |
| COPD | 31 | 25 | 6 | 0.46 |
| CKD | 15 | 12 | 3 | 0.77 |
| LVEF (%) | 49 ± 11 | 48 ± 10 | 53 ± 10 | <0.001 |
| rs1799983_GG | 158 | 115 | 43 | 0.36 |
| rs1799983_GT | 59 | 51 | 8 | 0.03 |
| rs1799983_TT | 145 | 106 | 39 | 0.46 |
BMI: body mass index; CV: cardiovascular; AF: atrial fibrillation; COPD: chronic obstructive pulmonary disease; CKD: chronic kidney disease; LVEF: left ventricular ejection fraction; rs1799983: polymorphism for the gene nitric oxide synthase 3.