Table 3.
Summary of randomized trials on the effect of diet during pregnancy on the risk of gestational diabetes mellitus
|
Ref.
|
Design
|
Comparison
|
No. of participants (studies)
|
RR of GDM (95%CI)
|
| Song et al[54], 2016 | Meta-analysis, 27 RCTs (11487 women) | Lifestyle intervention of diet, PA or both vs standard management | 11487 (27) | 0.82 (0.70-0.95) |
| PA plus diet vs standard management | 6047 (14) | 0.85 (0.70-1.03) | ||
| Diet only vs standard management | 1279 (5) | 0.80 (0.58-1.10) | ||
| Tieu et al[53], 2017 | Meta-analysis, 11 RCTs (2786 women) | Dietary recommendations vs standard treatment | 1279 (5 RCTs) | 0.60 (0.35-1.04); in overweight and obese women RR 0.39 (0.19-0.79) |
| Low-glycemic index (GI) diet vs medium- or high-GI dietary recommendations | 912 (4 RCTs) | 0.91 (0.63-1.31) | ||
| High-fiber diet vs standard dietary recommendations | 25 (1) | No association | ||
| Shepherd et al[55], 2017 | Meta-analysis, 23 RCTs (8918 women) | Combination of diet and exercise vs standard management | 6633 (19) | 0.85 (0.71-1.01) |
| Guo et al[56], 2019 | Meta-analysis, 47 RCTs (15745 women) | Lifestyle intervention (diet, exercise, and mixed interventions) vs standard management | 15745 (47) | 0.77 (0.69-0.87) |
| Diet alone vs standard management | 2838 (11) | 0.75 (0.60-0.95), |
RR: Relative risk; PA: Physical activity; RCTs: Randomized clinical trials; CI: Confidence interval; GDM: Gestational diabetes mellitus.