Table 6.

Major loci associated with changes in serum 25-hydroxyvitamin D concentration

Chromosome	SNP	Gene symbol	Protein	P value
4p12	rs2282679	GC	Vitamin D binding protein	1.9 × 10-109
11q12	rs12785878	DHCR7	7-dehydrocholsterol reductase	2.1 × 10-27
11p15	rs10741657	CYP2R1	1-alpha-hydroxylase	3.3 × 10-20
20q13	rs6013897	CYP24A1	1,25-dihydroxyvitamin D3 24-hydroxylase	6.0 × 10-10

Adapted from Wang et al[126]. SNP: Single nucleotide polymorphism.