Table 3.
Multivariable regression models for TH BMD change from baseline (%), 1 year after parathyroidectomy, in patients with PHPT.
| Change in TH BMD from Baseline (%) | Model I | Model II | Model III | |||
|---|---|---|---|---|---|---|
| Variables | β coefficient (95% CI) |
p-value | β coefficient (95% CI) |
p-value | β coefficient (95% CI) |
p-value |
| miR-19b-3p | −1.55 (−2.99 to −0.10) |
0.038 | −1.31 (−2.71 to 0.08) |
0.062 | −1.08 (−2.26 to 0.10) |
0.067 |
| miR-122-5p | −2.12 (−3.29 to −0.95) |
0.002 | −3.00 (−4.56 to −1.45) |
0.002 | −2.60 (−3.88 to −1.32) |
0.003 |
| miR-375 | −1.61 (−3.08 to −0.15) |
0.034 | −1.62 (−2.80 to −0.44) |
0.013 | −1.34 (−2.25 to −0.43) |
0.011 |
Model 1: No adjustment. Model 2: Adjusted for age and sex. Model 3: Adjusted for age, sex, PTH, and P1NP. Abbreviations: 95% CI, 95% confidence interval; PTH, parathyroid hormone transformed by natural logarithm; P1NP, procollagen type 1 N-terminal propeptide.