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. 2021 Aug 30;13(9):1722. doi: 10.3390/v13091722

Figure 4.

Figure 4

Inhibition curve of Sinefungin. Capped m7Gp3A-RNA was treated with nsp10-nsp16 and SAM at various concentrations of Sinefungin. After reaction, RNA was cleaved by nuclease P1 and analyzed, and the dimethylated cap (m7Gp3Am) was quantified by LC-MS. The measurement was performed in triplicate.