Table 1.
Summary table of standardization guidelines/regulations set for image acquisition and reconstruction parameters across various centers.
| Standardization of Image Acquisition and Reconstruction Parameters across Various Centers Related to Clinical Trials | |||
|---|---|---|---|
| Reference | Data | Variation Across | Summary |
| Mottet et al. [42] Cornford et al. [43] (ESTRO) |
CT and MRI images (prostate cancer) | NA | Provided guidelines procedures and methods for image-guided radiation therapy (IGRT) in prostate cancer |
| Boellaard et al. [45] (EARL) |
PET imaging | Scan acquisition, image processing, image interpretation | Provides guideline/regulations for oncology |
| Luh et al. [48] (ASTRO) |
NA | NA | Developed a ‘practice parameter’ for IGRT, and provided quality assurance standards, personnel qualifications, indications and guided documentation for imaging |
| Sachs et al. [51] | CT and MRI images | CT and MRI protocols | Reduced the number of MRI protocols from 168 to 66 and CT protocols from 248 to 97 across scanners and centers by selecting an appropriate clinical-driven protocol and standardization process |
| Center for Drug Evaluation and Research (FDA) [52] | NA | Image acquisition parameters | Provided guidelines to focus on image acquisition in clinical trials conducted to support authorization of drugs and biological products |