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. 2021 Sep 19;11(9):1239. doi: 10.3390/brainsci11091239

Figure 3.

Figure 3

Aβ42, τT and τp-181 CSF levels in FTD, ALS and FTD/ALS patients carrying either the p.Asn207Ser (p.N207S) exonic C9orf72 variant (A) or the rare intronic C9orf72 variants (B,C). (A) Here we compared Aβ42 CSF levels in FTD patients carrying the p.Asn207Ser (p.N207S) exonic C9orf72 variant to patients without this variant and no statistically significant difference was found. (B) FTD patients that were carriers of rare intronic variants in the C9orf72 gene had lower CSF levels of τT. (C) CSF levels of τp-181 did not differ in FTD and/or ALS patients carrying rare C9orf72 intronic variants.