Figure 4.

Cellular uptake of 25 µM compounds 1–11 into the MCF-7 cells at pH 7.4 in the absence (black bars), and presence of efflux inhibitors (50 µM), elacridar (P-gp and BCRP inhibitor, white bars), and MK-571 (unselective MRP inhibitor, dotted bars). The data is presented as mean ± SD, n = 3 (* p < 0.05, ** p < 0.01, *** p < 0.001, one-way ANOVA, followed by Tukey’s test).