Table 1.
Inspected DEGs involved in stress.
| Gene | HCN2-CTR Expression |
HCN2-SARS-CoV-2 Expression | Fold Change | q-Value | Biological Process |
|---|---|---|---|---|---|
| CDKN2A | 53.60 | 86.25 | 0.69 | 3.10 × 10−4 | Oxidative stress Induced senescence |
| EZH2 | 96.00 | 53.75 | −0.84 | 1.73 × 10−5 | Oxidative stress Induced senescence |
| FOS | 172.00 | 11.25 | −3.93 | 1.75 × 10−28 | Oxidative stress Induced senescence |
| JUN | 413.61 | 209.99 | −0.98 | 6.81 × 10−26 | Oxidative stress Induced senescence |
| MAP3K5 | 50.40 | 35.00 | −0.53 | 4.48 × 10−2 | Oxidative stress Induced senescence |
| MOV10 | 493.61 | 324.99 | −0.60 | 1.42 × 10−14 | Oxidative stress Induced senescence |
| ASF1A | 46.40 | 67.50 | 0.54 | 1.18 × 10−2 | DNA damage/telomere stress-induced senescence |
| CCNA2 | 92.00 | 53.75 | −0.78 | 8.33 × 10−5 | DNA damage/telomere stress-induced senescence |
| CCNE1 | 82.40 | 53.75 | −0.62 | 2.50 × 10−3 | DNA damage/telomere stress-induced senescence |
| CCNE2 | 40.80 | 5.00 | −3.03 | 6.73 ×10−8 | DNA damage/telomere stress-induced senescence |
| HIRA | 11.20 | 21.25 | 0.92 | 2.54 × 10−2 | DNA damage/telomere stress-induced senescence |
| HMGA1 | 5586.56 | 3476.15 | −0.68 | 1.20 × 10−194 | DNA damage/telomere stress-induced senescence |
| HMGA2 | 1301.64 | 338.74 | −1.94 | 4.68 × 10−183 | DNA damage/telomere stress-induced senescence |
| CXCL8 | 25.60 | 73.75 | 1.53 | 7.78 × 10−11 | Oxidative stress Alteration |
| NOXA1 | 3.20 | 8.75 | 1.45 | 4.49 × 10−2 | Oxidative stress Alteration |
| PMAIP1 | 23.20 | 37.50 | 0.69 | 1.97 × 10−2 | Oxidative stress Alteration |
| PTGS2 | 21.6 | 343.74 | 3.99 | 3.73 × 10−82 | Oxidative stress Alteration |
The fold-change columns are based on log2(HCN2-CTR expression/HCN2-SARS-CoV-2 expression). The values are rounded to the second decimal digit.