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. 2021 Sep 10;9(9):1924. doi: 10.3390/microorganisms9091924

Table 3.

Antibiotic resistance genes detected in Bacillus velezensis strain B25 genome.

B25 Gene Label Gene Symbol Product Antibiotic Class Similarity with (Amino Acid Identity %)
BAMMD1_0254 lmrB Lincomycin resistance protein lincosamide IT45 (99.8%), FZB42 (99.4%), B168 (88.4%)
BAMMD1_0286 Mdr multidrug-efflux transporter aminonucleoside, fluoroquinolone IT45 (100%), FZB42 (99.6%), B168 (90.2%)
BAMMD1_0294 tmrB Tunicamycin resistance protein nucleoside IT45 (98.5%), FZB42 (98.5%), B168 (77%)
BAMMD1_0514 Cfr Ribosomal RNA large subunit methyltransferase oxazolidinone, lincosamide, streptogramin, phenicol IT45 (99.7%), FZB42 (97.4%)
BAMMD1_0534 vmlR Ribosome protection protein streptogramin, oxazolidinone, lincosamide, pleuromutilin, phenicol, tetracycline, macrolide IT45 (100%), FZB42 (98.3%), B168 (71%)
BAMMD1_0665 aadK Aminoglycoside 6-adenylyltransferase aminoglycoside IT45 (99.3%), B168 (63%)
BAMMD1_1112 Bla Metallo-beta-lactamase type 2 Beta-lactam IT45 (99.6%), FZB42 (97.2%)
BAMMD1_1128 penN Beta-lactamase Beta-lactam IT45 (99.7%), FZB42 (95.7%), B168 (88.5%)
BAMMD1_2341 tetB Tetracycline resistance protein tetracycline IT45 (99.3%), B168 (86.7%)