Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Schematic representation showing the dynamic role of osteocytes in the regulation of healthy and dysregulated bone. Beta-adrenergic receptor (Adrβ2), hydroxyapatite (HA), osteocalcin (OCN), osteoprotegerin (OPG), receptor activator of nuclear factor kappa-β ligand (RANKL), and reactive oxygen species (ROS). Red lines indicate hyperinsulinaemia-driven pathology pathways. Healthy physiology indicated with blue and purple lines.
