Figure 1.

In vitro evaluation of the effect exerted by RUT (1, 5, 10, 25, and 50 µM) after 24 h of treatment on (A) RPMI-7951 and (B) SK-MEL-28 malignant melanoma cells’ viability by performing the MTT assay. Data are presented as viability percentages (%) normalized to Control and expressed as mean values ± SD of three independent experiments performed in triplicate. The statistical differences between Control and the treated group were verified by applying the one-way ANOVA analysis followed by Dunnett’s multiple comparisons post-test (* p < 0.1; ** p < 0.01; *** p < 0.001; **** p < 0.0001).