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. 2021 Sep 6;10(9):1422. doi: 10.3390/antiox10091422

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Oxidative stress (induced by tBHP) reduced increased serotonin and melatonin levels in the ovary and changed body amino acid biosynthesis and metabolism. (A) Ovarian tissue melatonin levels. (B) Ovarian tissue serotonin levels. (C) Description of the different metabolites between OS and CON group by volcano plot. (D) KEGG pathway enrichment of target metabolites. (E) Spearsman Correlationship between metabolites and microbiota. Statistical significance was evaluated by the Student’s t-test, * p < 0.05.