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. 2021 Sep 10;22(18):9778. doi: 10.3390/ijms22189778

Table 2.

A comparison between antibodies and nanobodies in molecular imaging, diagnosis and surgery.

Antibody Nanobody
Slow and non-specific tumor accumulation Rapid and specific tumor accumulation
Slow imaging time (1–6 days) Rapid imaging time (1–3 h)
Increased background-to-tumor ratio High tumor-to-background ratio
Slow clearance Rapid clearance
Less accurate visualization of tumor, metastasized lesions and tumor boarders More accurate visualization of tumor, metastasized lesions and tumor boarders