Figure 1.

Ultrastructure illustrations of membrane contacts in hepatocytes. Primary mouse hepatocytes were cultured for 24 h, then analyzed by EM. (A) Representative EM image of a primary cultured hepatocyte. (B,C) Enlarged images from the boxed areas in A. White arrows denote mitochondria–ER contact and black arrows denote ER–LD contact. LD: lipid droplet; M: mitochondria; N: nucleus. All of the EM imaging data in this manuscript are from the authors’ lab and have not been previously published. Bar: 500 nm.