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Summary of protein-coding genes associated with identified ACPA and RA DMRs, and those associated with RA causal SNPs from GWAS Catalog.
| Source | # of Mapped Genes | Overlap with GWAS Genes |
|---|---|---|
| 585 SNPs from GWAS Catalog | 295 | |
| 814 ACPA-associated DMRs | 403 |
HLA-DRB1, HLA-DRB5 ERICH1, KIF26B, SPAG1 DUSP22, DOCK1, NTM DGKQ, PRDM16, RAD51B TP73, SLC9A9, ZNF595 |
| 843 RA-associated DMRs | 376 |
ERICH1, ZNF595, SPAG1, TP73 PADI4, CARD9, CTIF |
