Table 7.

Gene symbols involved in cell–cell adhesion (GO:0098609) for each of the profiled gene sets, with the number of associated SNPs/DMRs.

Gene List	Genes Involved	#SNPs/DMRs Associated
GWAS Catalog	PTPN22, CYRIB, SRC, HLA-DQB1, ETS1, ZFP36L1, PTPN2 RUNX1, TNFSF4, IL2RA, PRKCQ, GATA3, SWAP70, BAD CD83, BLK, CTLA4, ICOS, CXCL13, SH2B3, CCR2, CD28 TNIP1, HLA-DRB1, CDH18, NOTCH4, PCDH15, PTPRM SFTPD, FCGR2B, IL2, IL21, TRAF6, DLG2, RASGRP1 HLA-DRA, PTPRC, CD200R1, KIF26B, DPP4, ICAM3 PTPN11, EMCN	86
ACPA-associated DMRs	HLA-DRB1, MDGA1, C1QTNF1, AP3D1, CLSTN1, CNTN4 CELSR3, ALOX12, SCRIB, CRB2, PKP3, MAG, PLPP3, KIF26B PDGFRA, MAD1L1, SDK1, CDHR3, DSCAML1, UBASH3B JAM3, SDK2, MBP, PCDHA8, PCDHB8, PCDHB16, PCDHB10 PCDHB13, PCDHB15, PCDHGB3, PCDHGA12, PCDHA13 PCDHA2, PCDHA7, PCDHB3, PCDHB4, PCDHB5, PCDHB6 PCDHB7, PCDHB11, PCDHB12, PCDHGA1, PCDHGA5 PCDHA1, PCDHA3, PCDHA4, PCDHA5, PCDHA6, PCDHA9 PCDHA10, PCDHA11, PCDHA12, PCDHGA2, PCDHGA3 PCDHGB1, PCDHGA4, PCDHGA7, PCDHGB4, PCDHGA8 PCDHGB5, PCDHGA6, PCDHGA9, PCDHGB6, PCDHGA10 PCDHGB2, PCDHGB7, PCDHGA11	55
RA-associated DMRs	CD160, FGL1, RDX, PIEZO1, AP3D1, MEGF10, SCRIB, ITGA8 PKP3, LRRC32, MAG, CELSR1, PRKCZ, GLI2, NCK1, PDGFRA MAD1L1, SDK1, CDHR3, UBASH3B, GPC6, NTN1, MBP, PAK4 CDH4, RIPOR2, PCDHA3, PCDHB3, PCDHB8, PCDHB16 PCDHGA3, PCDHGB1, PCDHGB2, PCDHGB3, PCDHGA8 PCDHGB4, PCDHA2, PCDHA12, PCDHB7, PCDHB10, PCDHB11 PCDHB13, PCDHB14, PCDHGA1, PCDHGA2, PCDHGA4 PCDHGA6, PCDHGA7, PCDHA1, PCDHA4, PCDHA5, PCDHA6 PCDHA7, PCDHA8, PCDHA9, PCDHA10, PCDHA11, PCDHGA5	49