Figure 1.

Activity of neutrophils isolated 7 days before, 2 h and 24 h after implantation (experimental: 8 sheep) compared to control groups of neutrophils isolated at the same time points from animals from control groups (control: 4 sheep). C: control group, E: experimental group. The neutrophil response to Ti implant insertion, with or without stimulation with AMP extract; (a) ALP release from neutrophils, (b) NO generation release, (c) superoxide generation in the inflammatory phase of the repair process assessed at two measurements, after 30 min and 22 h incubation at 37 °C and 5% CO₂. Data present mean values ± SE of at least three replicates for each bar. * p < 0.05 compared to cultures of neutrophils from the control group at the same time points. ** p < 0.01.