Figure 7.

Activity of neutrophils isolated 4 and 10 months after implantation (experimental—8 sheep) compared to control groups of neutrophils isolated at the same time points from animals from control groups (control: 4 sheep). C—control group, E—experimental group. The response to implantation and treatment with two concentrations of PTX (1 and 100 µg/mL); (a) elastase release from neutrophils, (b) MPO release, (c) ALP release, (d) NO generation, (e) superoxide generation assessed at two time points: 4 and 10 months after implantation. Data present mean values ± SE of at least three replicates for each bar. * p < 0.05 compared to cultures of neutrophils without stimulation (0 µg/mL) at the same time points.